Τίτλος:
The Cretan Aging Cohort: Cohort Description and Burden of Dementia and Mild Cognitive Impairment
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Our aim was to explore the burden of dementia in the Cretan Aging Cohort, comprised of 3140 persons aged ≥60 years (56.8% women, 5.8 ± 3.3 years formal education, 86.2% living in rural areas) who attended selected primary health-care facilities on the island of Crete, Greece. In the first study phase, a formal diagnosis of dementia had been reached in 4.0% of the participants. However, when selected 505 participants underwent thorough neuropsychiatric evaluation in the second phase of this study (344 with Mini-Mental State Examination [MMSE] <24 and 161 with MMSE ≥24), and results were extrapolated to the entire cohort, the prevalence of dementia and mild cognitive impairment was estimated at 10.8% (9.7%-11.9%) and 32.4% (30.8%-34.0%), respectively. Using both the field diagnostic data and the extrapolated data, the highest dementia prevalence (27.2%) was found in the 80- to 84-year-old group, who also showed the lowest educational level, apparently due to lack of schooling during World War II. © The Author(s) 2018.
Συγγραφείς:
Zaganas, I.V.
Simos, P.
Basta, M.
Kapetanaki, S.
Panagiotakis, S.
Koutentaki, I.
Fountoulakis, N.
Bertsias, A.
Duijker, G.
Tziraki, C.
Scarmeas, N.
Plaitakis, A.
Boumpas, D.
Lionis, C.
Vgontzas, A.N.
Περιοδικό:
American Journal of Alzheimer's Disease and other Dementias
Εκδότης:
SAGE Publications Inc.
Λέξεις-κλειδιά:
adult; aged; aging; Article; clinical trial; cognition; cohort analysis; dementia; disease burden; female; follow up; human; Independent Activities of Daily Living scale; major clinical study; male; middle aged; mild cognitive impairment; Mini Mental State Examination; phase 1 clinical trial; phase 2 clinical trial; prevalence; questionnaire; semi structured interview; very elderly; cognitive defect; cost of illness; dementia; dementia assessment; Greece, Aged; Aged, 80 and over; Aging; Cognitive Dysfunction; Cohort Studies; Cost of Illness; Dementia; Female; Greece; Humans; Male; Mental Status and Dementia Tests; Middle Aged; Prevalence
DOI:
10.1177/1533317518802414
