Περίληψη:
Objective: The objective of this study was to characterise international trends in the use of psychotropic medication, psychological therapies, and novel therapies used to treat obsessive–compulsive disorder (OCD). Methods: Researchers in the field of OCD were invited to contribute summary statistics on the characteristics of their samples. Consistency of summary statistics across countries was evaluated. Results: The study surveyed 19 expert centres from 15 countries (Argentina, Australia, Brazil, China, Germany, Greece, India, Italy, Japan, Mexico, Portugal, South Africa, Spain, the United Kingdom, and the United States) providing a total sample of 7,340 participants. Fluoxetine (n = 972; 13.2%) and fluvoxamine (n = 913; 12.4%) were the most commonly used selective serotonin reuptake inhibitor medications. Risperidone (n = 428; 7.3%) and aripiprazole (n = 415; 7.1%) were the most commonly used antipsychotic agents. Neurostimulation techniques such as transcranial magnetic stimulation, deep brain stimulation, gamma knife surgery, and psychosurgery were used in less than 1% of the sample. There was significant variation in the use and accessibility of exposure and response prevention for OCD. Conclusions: The variation between countries in treatments used for OCD needs further evaluation. Exposure and response prevention is not used as frequently as guidelines suggest and appears difficult to access in most countries. Updated treatment guidelines are recommended. © 2019 John Wiley & Sons, Ltd.
Συγγραφείς:
Brakoulias, V.
Starcevic, V.
Albert, U.
Arumugham, S.S.
Bailey, B.E.
Belloch, A.
Borda, T.
Dell'Osso, L.
Elias, J.A.
Falkenstein, M.J.
Ferrao, Y.A.
Fontenelle, L.F.
Jelinek, L.
Kalogeraki, L.
Kay, B.
Laurito, L.D.
Lochner, C.
Maina, G.
Marazziti, D.
Martin, A.
Matsunaga, H.
Miguel, E.C.
Morgado, P.
Mourikis, I.
Pasquini, M.
Perez Rivera, R.
Potluri, S.
Reddy, J.Y.C.
Riemann, B.C.
do Rosario, M.C.
Shavitt, R.G.
Stein, D.J.
Viswasam, K.
Wang, Z.
Fineberg, N.A.
Λέξεις-κλειδιά:
amisulpride; aripiprazole; benzodiazepine; carbamazepine; chlorpromazine; citalopram; clomipramine; desvenlafaxine; duloxetine; escitalopram; fluoxetine; fluvoxamine; haloperidol; lamotrigine; lithium; lurasidone; memantine; mirtazapine; olanzapine; paliperidone; paroxetine; quetiapine; riluzole; risperidone; sertraline; topiramate; unindexed drug; valproic acid; venlafaxine; ziprasidone; benzodiazepine derivative; neuroleptic agent; serotonin uptake inhibitor, adolescent; Argentina; Article; Australia; brain depth stimulation; Brazil; China; female; gamma knife surgery; Germany; Greece; human; India; Italy; Japan; major clinical study; male; Mexico; obsessive compulsive disorder; Portugal; priority journal; psychosurgery; radiosurgery; South Africa; Spain; transcranial magnetic stimulation; United Kingdom; United States; adult; international cooperation; middle aged; obsessive compulsive disorder, Adult; Antipsychotic Agents; Benzodiazepines; Deep Brain Stimulation; Female; Humans; Internationality; Male; Middle Aged; Obsessive-Compulsive Disorder; Psychosurgery; Serotonin Uptake Inhibitors