Τίτλος:
The role of internal limiting membrane peeling in epiretinal membrane surgery: A randomised controlled trial
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Purpose To compare the anatomical and functional outcomes after primary idiopathic epiretinal membrane (ERM) peeling with or without internal limiting membrane (ILM) peeling. Design A two-centre randomised, controlled clinical trial with 12 months of follow-up. Methods One hundred and two eyes of 102 patients were included in the analysis and were randomised into two groups (ILM peeling (P) and non-ILM peeling (NP) group). Inclusion criteria were: Idiopathic ERM confirmed on optical coherence tomography, age ≥18 years, binocular distortion, best-corrected visual acuity (BCVA) ≤90 ETDRS letters, intraocular pressure ≤23 mm Hg and informed consent. The primary outcome measure was the mean change in the ETDRS distance BCVA at 12 months' follow-up for each group. Results The mean change in distance BCVA at 12 months was 0.30±0.24 logMAR (15 ETDRS letters) in the P group and 0.31±0.23 logMAR (14 ETDRS letters) in the NP group, a change that was not statistically significant (p=0.84). No statistically significant differences were observed when comparing the changes in distance BCVA, the changes in metamorphopsia (Amsler grid) and the changes in central retinal thickness between the two groups at any of the time points studied. Conclusions Our analysis suggests that ILM peeling in idiopathic ERM surgery does not result in better visual improvement. The more frequent presence of an uninterrupted interdigitation zone in the P group did not result in a better functional outcome of our patients. No recurrent ERMs were noted in either group. © 2016 Published by the BMJ Publishing Group Limited.
Συγγραφείς:
Tranos, P.
Koukoula, S.
Charteris, D.G.
Perganda, G.
Vakalis, A.
Asteriadis, S.
Georgalas, I.
Petrou, P.
Περιοδικό:
British Journal of Ophthalmology
Εκδότης:
BMJ Publishing Group
Λέξεις-κλειδιά:
adult; age distribution; aged; Amsler chart; Article; best corrected visual acuity; binocular distortion; central retinal thickness; comparative study; controlled study; epiretinal membrane; epiretinal membrane peeling; female; follow up; functional assessment; human; informed consent; internal limiting membrane peeling; intraocular pressure; major clinical study; male; metamorphopsia; multicenter study; optical coherence tomography; outcome assessment; postoperative care; priority journal; randomized controlled trial; retina surgery; visual system parameters; clinical trial; epiretinal membrane; pathology; procedures; retina; retrospective study; time factor; treatment outcome; visual acuity; vitrectomy, Aged; Epiretinal Membrane; Female; Follow-Up Studies; Humans; Male; Retina; Retrospective Studies; Time Factors; Tomography, Optical Coherence; Treatment Outcome; Visual Acuity; Vitrectomy
DOI:
10.1136/bjophthalmol-2016-309308
