Τίτλος:
Seroprevalence of hepatitis E in HIV infected patients in Greece
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
HEV infection is an emerging public health problem worldwide Data concerning HEV infection in HIV+ patients in Greece is scare. The aim of the study was to determine HEV seroprevalence in patients with HIV infection in Greece. We studied 243 HIV(+) patients 214 men (88%) and 29 women (12%) with a median age of 45 years (range 19-83) who attended the HIV unit of Pathophysiology Department of Laikon General Hospital in Athens for the presence of anti-HEV IgG antibodies with (EIA) (EIA HEV IgG, Adaltis, Rome, Italy Eighteen/243 patients (7.3%) were positive for HEV IgG antibodies, a seroprevalence that was not different from that described for the blood donors group from Greece There was no difference of the presence of HbsAg, hepatitis C and hepatitis A between the HEV(+) and HEV(-) patients. There was no statistically significant difference between the HEV(+) and HEV(-) group in terms of HIV acquisition, sexual orientation, median duration of HIV infection, ART treatment, or duration of ART. Only the median age of HEV(+) was 52years (35-78) while that of HEV(-) was 44years (19-83)(P=0.03). Only 2/18(11.1%) HEV(+) HIV(+) patients had abnormal ALT and AST values. The seroprevalence of hepatitis E in HIV(+) patients in Greece seems to be the same with that of the general population thus implying that HIV infection is not a risk factor for HEV infection and only age shows a positive correlation with seropositivity. © 2015 Wiley Periodicals, Inc.
Συγγραφείς:
Politou, M.
Boti, S.
Androutsakos, T.
Valsami, S.
Pittaras, T.
Kapsimali, V.
Περιοδικό:
Journal of Medical Virology
Εκδότης:
John Wiley and Sons Inc
Λέξεις-κλειδιά:
hepatitis B surface antigen; hepatitis C antibody; immunoglobulin G; hepatitis antibody; hepatitis B surface antigen; hepatitis C antibody, adult; age; aged; antiviral therapy; Article; CD4 lymphocyte count; controlled study; correlational study; disease association; disease duration; female; Greece; hepatitis A; hepatitis E; human; Human immunodeficiency virus infection; major clinical study; male; prospective study; risk factor; seroprevalence; sexual orientation; treatment duration; virus load; blood; blood donor; complication; hepatitis E; Hepatitis E virus; HIV Infections; immunology; middle aged; sexual behavior; very elderly; virology; young adult, Hepatitis C virus, Adult; Age Factors; Aged; Aged, 80 and over; Blood Donors; Female; Greece; Hepatitis Antibodies; Hepatitis B Surface Antigens; Hepatitis C Antibodies; Hepatitis E; Hepatitis E virus; HIV Infections; Humans; Male; Middle Aged; Seroepidemiologic Studies; Sexual Behavior; Young Adult
