Mixed cryoglobulinemia in Greece: Primary disorders in 10 cases

Επιστημονική δημοσίευση - Άρθρο Περιοδικού uoadl:3005006 23 Αναγνώσεις

Μονάδα:
Ερευνητικό υλικό ΕΚΠΑ
Τίτλος:
Mixed cryoglobulinemia in Greece: Primary disorders in 10 cases
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Mixed cryoglobulinemia (MC) is a systemic disorder whose pathogenesis is based on the presence of serum cryoglobulins. The purpose of this study was to evaluate on a prospective basis patients presenting with MC with regard to the clinical manifestations and the underlying disorders. We present ten patients with MC, who were diagnosed and followed up during a one year period in the Division of autoimmune rheumatic diseases (Clinical Department of Pathophysiology). MC was associated with hepatitis C virus (HCV) infection in two cases, with hepatitis B virus (HBV) infection in six, one patient had both HCV and evidence of HBV infection, while the remaining three patients fulfilled European classification criteria for diagnosis of Sjogren's syndrome (SS). In all ten cases, the presence of an underlying factor was identified, being either vital or autoimmune. It is concluded therefore that all patients presenting with MC should be completely evaluated for a hepatitis virus infection or an autoimmune or lymphoproliferative disorder. Furthermore, since the initiation of the process of MC is triggered by many factors, research should be directed towards the identification of the underlying common denominator.
Έτος δημοσίευσης:
1997
Συγγραφείς:
Boki, K.A.
Linardaki, G.D.
Galanopoulou, V.
Vaiopoulos, G.
Tzioufas, A.G.
Moutsopoulos, H.M.
Περιοδικό:
Scandinavian Journal of Rheumatology
Εκδότης:
Informa Healthcare
Τόμος:
26
Αριθμός / τεύχος:
4
Σελίδες:
280-286
Λέξεις-κλειδιά:
adult; aged; antibody detection; article; autoimmunity; clinical article; cryoglobulinemia; disease association; female; Greece; hepatitis B; Hepatitis B virus; hepatitis C; Hepatitis C virus; human; intravenous drug administration; male; pathogenesis; priority journal; serodiagnosis; Sjoegren syndrome; virus hepatitis
Επίσημο URL (Εκδότης):
DOI:
10.3109/03009749709105317
Το ψηφιακό υλικό του τεκμηρίου δεν είναι διαθέσιμο.