Τίτλος:
Study of the glycogenolytic action of platelet activating factor in Tetrahymena pyriformis
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
1. A novel action of AGEPC on non-inflammatory cells was revealed, namely the ability to stimulate glycogenolysis in Tetrahymena pyriformis cells. 2. The glycogenolytic effect of AGEPC seems to be dependent on Ca2+ transport and regulation, thus the effects are completely inhibited by Verapamile and partially by EGTA. 3. The influence of Propranolol, Labetalol, Atenolol and Theophylline in the glycogenolytic effect of AGEPC are also studied. 4. Our findings suggest that the AGEPC promoted glycogenolysis in Tetrahymena through a mechanism distinct from that of catecholamines. © 1992.
Συγγραφείς:
Tsangaris, G.Th.
Demopoulos, C.A.
Tsoukatos, D.C.
Kapoulas, V.M.
Περιοδικό:
Comparative Biochemistry and Physiology Part C: Comparative Pharmacology
Λέξεις-κλειδιά:
atenolol; egtazic acid; glycerophospholipid; labetalol; propranolol; theophylline; thrombocyte activating factor; verapamil, animal experiment; article; glycogenolysis; nonhuman; priority journal; tetrahymena pyriformis, Animal; Atenolol; Calcium; Cyclic AMP; Glucose; Glycogen; Labetalol; Platelet Activating Factor; Propranolol; Tetrahymena pyriformis
DOI:
10.1016/0742-8413(92)90149-2
