Τίτλος:
Organochlorine pollutants’ levels in hair, amniotic fluid and serum samples of pregnant women in Greece. A cohort study
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Persistent organic pollutants are synthetic chemicals highly resistant to degradation with strong tendency to bioaccumulation. Assessment of human exposure to these compounds is crucial for public health protection, especially during vulnerable periods. The aim of the present cohort study was to evaluate the level of contamination to PCBs, o,p’- and p,p’-DDE, o,p’ and p,p’-DDD, o,p’ and p,p’-DDT and HCB in pregnant women. Hair, amniotic fluid and serum samples were collected and analyzed by HS-SPME-GCMS. The most detected analytes in amniotic fluids were p,p’-DDE, p,p’-DDD, o,p’-DDE and PCB101, in serum p,p’-DDE, HCB and PCB101 and in hair p,p’-DDE, HCB and PCB101. The levels of HCB and PCB101 in amniotic fluids were positively correlated with those in hair. Higher levels of DDDs and DDTs in hair samples and PCB28 in amniotic fluids were observed in smoker pregnant women. Gestation age was inversely proportional with the detected levels of PCB101 in all tested samples. © 2019 Elsevier B.V.
Συγγραφείς:
Barmpas, M.
Vakonaki, E.
Tzatzarakis, M.
Sifakis, S.
Alegakis, A.
Grigoriadis, T.
Sodré, D.B.
Daskalakis, G.
Antsaklis, A.
Tsatsakis, A.
Περιοδικό:
Environmental Toxicology and Pharmacology
Λέξεις-κλειδιά:
1,1 dichloro 2,2 bis(4 chlorophenyl)ethane; 1,1 dichloro 2,2 bis(4 chlorophenyl)ethylene; organochlorine pesticide; chlorinated hydrocarbon; chlorphenotane; pesticide; polychlorinated biphenyl, adult; amnion fluid; Article; blood level; female; gestational age; Greece; hair level; human; major clinical study; persistent organic pollutant; pregnant woman; priority journal; smoking; amnion fluid; chemistry; hair; maternal exposure; metabolism; pollutant; pregnancy, Adult; Amniotic Fluid; DDT; Dichlorodiphenyl Dichloroethylene; Environmental Pollutants; Female; Greece; Hair; Humans; Hydrocarbons, Chlorinated; Maternal Exposure; Pesticides; Polychlorinated Biphenyls; Pregnancy
DOI:
10.1016/j.etap.2019.103279
