Τίτλος:
Hashish smoking and T-lymphocytes
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
To investigate the effect of long term hashish use on T-lymphocytes we have measured the incorporation of14C-thymidine by peripheral blood lymphocytes, unstimulated and stimulated by phytohemagglutinin, as well as the proportion and number of E-rosettes in 12 healthy male chronic users of the drug before and after a smoking session, and in 15 control subjects. The results show that hashish smoking does not impair the response of lymphocytes to PHA, at least at the concentration of PHA used. Furthermore there is a possibility that among chronic users a hashish smoking session may have a slight stimulatory effect. © 1978 Springer-Verlag.
Συγγραφείς:
Kaklamani, E.
Trichopoulos, D.
Koutselinis, A.
Drouga, M.
Karalis, D.
Περιοδικό:
Archives of Toxicology
Λέξεις-κλειδιά:
cannabinoid; cannabis; phytohemagglutinin; radioisotope; thymidine c 14; unclassified drug, article; drug dependence; human cell; inhalational drug administration; lymphocyte; lymphocyte transformation; normal human; rosette forming cell; smoking; T lymphocyte, Adult; Cannabis; Humans; Lectins; Lymphocyte Activation; Male; Middle Aged; Plant Lectins; Rosette Formation; T-Lymphocytes; Thymidine
