Chemical composition of Crepis foetida L. and C. rubra L. volatile constituents and evaluation of the in vitro anti-inflammatory activity of salicylaldehyde rich volatile fraction

Επιστημονική δημοσίευση - Άρθρο Περιοδικού uoadl:3009147 8 Αναγνώσεις

Μονάδα:
Ερευνητικό υλικό ΕΚΠΑ
Τίτλος:
Chemical composition of Crepis foetida L. and C. rubra L. volatile constituents and evaluation of the in vitro anti-inflammatory activity of salicylaldehyde rich volatile fraction
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
The genus Crepis L. (Asteraceae) comprises more than 200 currently recognized species. Several studies have been conducted on non-volatile phytochemicals of Crepis spp., featuring mainly sesquiterpene lactones and phenolic derivatives. Nevertheless, no report has been made on assessing the volatile constituents of the genus. Therefore, the present study is the first report to the chemical composition of the volatile constituents of two odoriferous Crepis spp., namely C. foetida L. and C. rubra L. Flowers and stems with leaves volatiles were analysed separately by gas chromatography coupled with mass spectrometry. In total, 37 volatile compounds were detected. Salicylaldehyde, carvacrol and aliphatic hydrocarbons are the main components of both C. foetida fractions, however C. rubra flowers are characterized by the abundance of β-sitosterol and eicosanoic acid, while the stems-leaves volatiles revealed to be more complex with hydrocarbons as main constituents. In addition, we investigated the salicylaldehyde rich volatile fraction for its in vitro activity on TNF-α induced ICAM-1 expression. © 2021
Έτος δημοσίευσης:
2021
Συγγραφείς:
Barda, C.
Grafakou, M.-E.
Kalpoutzakis, E.
Heilmann, J.
Skaltsa, H.
Περιοδικό:
Biochemical Systematics and Ecology
Εκδότης:
Elsevier Ireland Ltd
Τόμος:
96
Λέξεις-κλειδιά:
chemical composition; flower; gas chromatography; gene expression; plant extract; volatile organic compound, Asteraceae; Crepis; Crepis foetida; Crepis rubra
Επίσημο URL (Εκδότης):
DOI:
10.1016/j.bse.2021.104256
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