Τίτλος:
Sesquiterpene lactones from Centaurea thessala and Centaurea attica. Antifungal activity
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
The aerial parts of Centaurea thessala ssp. drakiensis and C. attica ssp. attica afforded, in addition to several known sesquiterpene lactones, two new eudesmanolides, 4-epi-sonchucarpolide and its 8-(3-hydroxy-4-acetoxy-2-methylene-butanoyloxy) derivative and one new eudesmane derivative, named atticin. The in vitro antifungal activity of most compounds was tested against nine fungal species, using the micro-dilution method. All the compounds tested showed great antifungal activity. (C) 2000 Elsevier Science Ltd.
Συγγραφείς:
Skaltsa, H.
Lazari, D.
Panagouleas, C.
Georgiadou, E.
Garcia, B.
Sokovic, M.
Περιοδικό:
Phytochemistry
Εκδότης:
Elsevier Ireland Ltd
Λέξεις-κλειδιά:
antifungal agent; Asteraceae; atticin; eudesmane derivative; eudesmanolide derivative; lactone; sesquiterpene; sesquiterpene lactone derivative; unclassified drug, antifungal activity; article; Aspergillus niger; controlled study; dilution; drug activity; drug isolation; drug structure; nonhuman; nuclear magnetic resonance spectroscopy; species difference; structure activity relation; structure analysis, Aspergillus niger; Asteraceae; Centaurea; Centaurea attica; Centaurea attica; Centaurea thessala; Centaurea thessala
DOI:
10.1016/S0031-9422(00)00254-5
