Τίτλος:
The Effect of Dobutamine Stress Testing on Vortex Formation Time in Patients Evaluated for Ischemia
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Vortex formation time (VFT) is a dimensionless index used to quantify duration of vortex ring formation during diastole. We sought to investigate the effect of pharmaceutical stress on VFT in patients evaluated for ischemia. For this purpose, a standard dobutamine stress echo (DSE) protocol was performed in 50 consecutive patients, and VFT was calculated at rest and at peak. VFT was calculated from echocardiography measurements using a previously developed mathematical equation. VFTi was calculated as the percentage of change of VFTpeak, compared with VFTrest. Mean VFTrest was 2.46 (0.73) and mean VFTpeak 1.67 (0.57) with mean VFTi − 30.0% (19.8). In 14 (28%) patients, an ischemic response (DSE+) was documented. VFTi was significantly lower in DSE+ patients a finding which remained significant in the multivariate analysis after adjusting for age, sex, hypertension, diabetes, history of coronary artery disease, and relative increase of heart rate during stress. [Figure not available: see fulltext.]. © 2020, Springer Science+Business Media, LLC, part of Springer Nature.
Συγγραφείς:
Dimitroglou, Y.
Aggeli, C.
Rapis, K.
Maragiannis, D.
Polytarchou, K.
Gatzoulis, K.
Tsiamis, E.
Tousoulis, D.
Περιοδικό:
Journal of Cardiovascular Translational Research
Λέξεις-κλειδιά:
beta 1 adrenergic receptor stimulating agent; dobutamine, aged; blood flow velocity; comparative study; coronary artery blood flow; cross-sectional study; diagnostic imaging; female; heart muscle ischemia; hemodynamics; human; male; middle aged; observer variation; pathophysiology; predictive value; prognosis; reproducibility; risk assessment; risk factor; stress echocardiography, Adrenergic beta-1 Receptor Agonists; Aged; Blood Flow Velocity; Coronary Circulation; Cross-Sectional Studies; Dobutamine; Echocardiography, Stress; Female; Hemodynamics; Humans; Male; Middle Aged; Myocardial Ischemia; Observer Variation; Predictive Value of Tests; Prognosis; Reproducibility of Results; Risk Assessment; Risk Factors
DOI:
10.1007/s12265-020-09998-z
