Τίτλος:
Unraveling the detoxification mechanism of 2,4-dichlorophenol by marine-derived mesophotic symbiotic fungi isolated from marine invertebrates
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Chlorophenols (CPs) are environmental pollutants that are produced through various anthropogenic activities and introduced in the environment. Living organisms, including humans, are exposed to these toxic xenobiotics and suffer from adverse health effects. More specifically, 2,4-dichlorophenol (2,4-DCP) is released in high amounts in the environment and has been listed as a priority pollutant by the US Environmental Protection Agency. Bioremediation has been proposed as a sustainable alternative to conventional remediation methods for the detoxification of phenolic compounds. In this work, we studied the potential of fungal strains isolated as symbionts of marine invertebrates from the underexplored mesophotic coral ecosystems. Hence, the unspecific metabolic pathways of these fungal strains are being explored in the present study, using the powerful analytical capabilities of a UHPLC-HRMS/MS. The newly identified 2,4-DCP metabolites add significantly to the knowledge of the transformation of such pollutants by fungi, since such reports are scarce. © 2019 by the authors.
Συγγραφείς:
Nikolaivits, E.
Agrafiotis, A.
Termentzi, A.
Machera, K.
Goff, G.L.
Álvarez, P.
Chavanich, S.
Benayahu, Y.
Ouazzani, J.
Fokialakis, N.
Topakas, E.
Λέξεις-κλειδιά:
2,4 dichlorophenol; 2,4-dichlorophenol; chlorophenol; phenol derivative; xenobiotic agent, Andaman Sea; Article; biocatalyst; biodiversity; bioremediation; chemical structure; coral; detoxification; enzyme activity; fungal metabolism; fungal strain; fungus identification; fungus isolation; marine invertebrate; mass spectrometry; Mediterranean Sea; nonhuman; Red Sea; symbiont; ultra performance liquid chromatography; xenobiotic metabolism; animal; Anthozoa; aquatic species; ecosystem; fungus; human; invertebrate; metabolism; microbiology; physiology; symbiosis; water pollutant, Animals; Anthozoa; Aquatic Organisms; Biodegradation, Environmental; Chlorophenols; Ecosystem; Fungi; Humans; Invertebrates; Metabolic Networks and Pathways; Phenols; Symbiosis; Water Pollutants, Chemical; Xenobiotics
