Τίτλος:
Successful Implantation and Live Birth Following Autologous Platelet-rich Plasma Treatment for a Patient with Recurrent Implantation Failure and Chronic Endometritis
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Background/Aim: Patients diagnosed with chronic endometritis (CE) may fail to respond to standard antibiotic treatment. The driver behind the approach reported here was the imperative need for alternative therapeutic solutions. Case Report: This case report presents a woman with CE and premature ovarian insufficiency having experienced repeated implantation failures following donated embryo transfers. The patient was diagnosed with CE through hysteroscopy, microbiological analysis and scanning electron microscopy. Following the suggested antibiotic treatment, she underwent a new embryo transfer, but with subsequent pregnancy loss. Following a second antibiotic scheme, all diagnostic procedures certified the persistence of CE. The patient underwent autologous, intrauterine platelet-rich plasma treatment and a subsequent embryo transfer. The diagnostic procedures indicated no signs of CE, while the embryo transfer resulted in a twin pregnancy and birth. Conclusion: Platelet-rich plasma may be employed as a first-line CE treatment, especially for patients who fail to respond to conventional antibiotic schemes. © 2019 International Institute of Anticancer Research. All Rights Reserved.
Συγγραφείς:
Sfakianoudis, K.
Simopoulou, M.
Nitsos, N.
Lazaros, L.
Rapani, A.
Pantou, A.
Koutsilieris, M.
Nikas, Y.
Pantos, K.
Περιοδικό:
In vivo (Athens, Greece)
Εκδότης:
International Institute of Anticancer Research
Λέξεις-κλειδιά:
antibiotic agent; chorionic gonadotropin; fluconazole; prolactin, adult; antibiotic therapy; antifungal therapy; Article; blastocyst; blood sampling; case report; chronic endometritis; clinical article; embryo transfer; endometriosis; endometritis; female; follicular phase; glucose tolerance test; human; hysteroscopy; light; limit of quantitation; live birth; luteal phase; medical history; menstrual cycle; premature ovarian failure; scanning electron microscopy; thrombocyte rich plasma; thyroid function test; transvaginal echography; twin pregnancy; uterus cavity; visual field; autotransplantation; endometritis; endometrium; female infertility; in vitro fertilization; nidation; pathophysiology; physiology; pregnancy; pregnancy outcome; pregnancy rate; veterinary medicine, Adult; Embryo Implantation; Embryo Transfer; Endometritis; Endometrium; Female; Fertilization in Vitro; Humans; Infertility, Female; Live Birth; Platelet-Rich Plasma; Pregnancy; Pregnancy Outcome; Pregnancy Rate; Transplantation, Autologous
DOI:
10.21873/invivo.11504
