Τίτλος:
Effects of pre- and postnatal exposure to 1880–1900 MHz DECT base radiation on development in the rat
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
In the present study, to evaluate the effects of wireless 1880–1900 MHz Digital Enhanced Communication Telephony (DECT) base radiation on fetal and postnatal development, Wistar rats were exposed at an average electric field intensity of 3.7 V/m, 12 h/day, during pregnancy. After parturition, a group of dams and offspring were similarly exposed for another 22 days. Controls were sham-exposed. The data showed that DECT base radiation exposure caused heart rate increase in the embryos on the 17th day of pregnancy. Moreover, significant changes on the newborns’ somatometric characteristics were noticed. Pyramidal cell loss and glia fibrilliary acidic protein (GFAP) over-expression were detected in the CA4 region of the hippocampus of the 22-day old pups that were irradiated either during prenatal life or both pre- and postnatally. Changes in the integrity of the brain in the 22-day old pups could potentially be related to developmental behavioral changes during the fetal period. © 2016 Elsevier Inc.
Συγγραφείς:
Stasinopoulou, M.
Fragopoulou, A.F.
Stamatakis, A.
Mantziaras, G.
Skouroliakou, K.
Papassideri, I.S.
Stylianopoulou, F.
Lai, H.
Kostomitsopoulos, N.
Margaritis, L.H.
Περιοδικό:
Reproductive Toxicology
Εκδότης:
ELSEVIER SCIENCE INC 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
Λέξεις-κλειδιά:
glial fibrillary acidic protein; glial fibrillary acid protein, rat; glial fibrillary acidic protein, animal cell; animal experiment; animal model; animal tissue; anthropometric parameters; Article; behavior change; body height; cell density; cell loss; comparative study; controlled study; crown rump length; dentate hilus; Digital Enhanced Communication Telephony base radiation; dosimetry; electric field intensity; electrical parameters; electromagnetic field; embryo; embryo development; exposure; female; fertility rate; fetus development; frontal cortex; growth; head length; head width; heart rate; histopathology; immunohistochemistry; immunoreactivity; litter size; molecular dynamics; newborn; newborn growth; nonhuman; parameters concerning the fetus, newborn and pregnancy; perinatal period; placenta width; postnatal development; postnatal exposure; prenatal exposure; prenatal period; protein analysis; protein expression; pyramidal nerve cell; radiation; radiation exposure; radiofrequency; rat; somatosensory cortex; Wistar rat; animal; brain; electromagnetism; fertility; fetus development; male; metabolism; pathology; pregnancy; telephone, Animals; Brain; Electromagnetic Fields; Embryonic Development; Female; Fertility; Fetal Development; Glial Fibrillary Acidic Protein; Heart Rate; Litter Size; Male; Pregnancy; Prenatal Exposure Delayed Effects; Rats, Wistar; Telephone
DOI:
10.1016/j.reprotox.2016.08.008
