Τίτλος:
Design and synthesis of some new pyranoxanthenones with cytotoxic activity
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
As part of a research program directed towards the design and synthesis of pyranoxanthones structurally related to acronycine, we present here the synthesis and cytotoxic activity of the pyranoxanthones 3 and 4 (X= H, Br; R= H, OMe; R'= H, Ac). Some of these compounds inhibit L1210 cell proliferation.
Συγγραφείς:
Ghirtis, K.
Pouli, N.
Marakos, P.
Skaltsounis, A.-L.
Leonce, S.
Atassi, G.
Caignard, D.H.
Περιοδικό:
Journal of Heterocyclic Chemistry
Λέξεις-κλειδιά:
acronine; bromine derivative; cytotoxic agent; pyranoxanthone derivative; unclassified drug, animal cell; article; cell proliferation; drug cytotoxicity; drug design; drug synthesis; mouse; nonhuman; reaction analysis; structure analysis
DOI:
10.1002/jhet.5570380121
