Τίτλος:
An educational intervention to optimize use of proton pump inhibitors in
a Greek university hospital
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Background Misuse of proton pump inhibitors (PPIs) is an alarming issue
for patients and healthcare systems.
Methods We conducted a 3-phase interventional, prospective study in a
Greek university hospital. During Phase I, we collected data from
patients’ records to evaluate the appropriate use of PPIs. During Phase
II, educational seminars about the proper use of PPIs were offered to
the medical staff. In Phase III we collected data from the records of
patients admitted to the hospital department with the highest rate of
inappropriate PPI administration during Phase I, to evaluate the
efficacy of the intervention. Inappropriate use was defined as either
PPI administration without indication, or lack of use despite adequate
indication. Appropriateness of PPI use was measured at admission, during
hospitalization and at discharge.
Results The rate of inappropriate PPI use was higher (51.7% and 48.6%)
during hospitalization than at admission (34.9% and 21.9%), but at
discharge was similar to pre-hospitalization levels (26.9% and 23.6%),
in Phases I and III, respectively. At discharge during Phase I, the
inappropriate use of PPIs was significantly higher (odds ratio 3.79,
95% confidence interval 1.98-7.19) for internal medicine patients than
for surgical patients. The educational intervention failed to reduce the
inappropriate use of PPIs during hospitalization (51.7% vs. 48.6%,
P=0.478) or at discharge (26.9% vs. 23.6%, P=0.391) in the internal
medicine patients.
Conclusions The rate of inappropriate PPI use is almost double during
hospitalization compared to the rates at admission and at discharge.
Implementation of an educational intervention failed to reduce the
inappropriate use of PPIs in internal medicine patients.
Συγγραφείς:
Lazaridis, Lazaros-Dimitrios
Rizos, Evripidis
Bounou, Lamprini
and Theodorou-Kanakari, Anna
Kalousios, Sotirios
Mavroeidi,
Electra-Antonia
Roma, Maria
Chatzidakis, Alexandros and
Vlachonicolou, Georgia
Miltiadou, Konstantinos
Gkolfakis,
Paraskevas
Tziatzios, Georgios
Triantafyllou, Konstantinos
Περιοδικό:
ANNALS OF GASTROENTEROLOGY
Εκδότης:
HELLENIC SOC GASTROENTEROLOGY
Λέξεις-κλειδιά:
Proton pump inhibitor; intervention; inappropriate use; misuse;
education
DOI:
10.20524/aog.2021.0654
