Τίτλος:
Not all melanomas are created equal: a review and call for more research
into nodular melanoma
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Among the histogenic subtypes of melanoma, nodular melanoma (NM) is the
major contributor for thicker and fatal melanomas and it has been
associated with melanoma-specific death in thin tumours, highlighting an
important subgroup of `aggressive thin' melanomas. This review provides
a synthesis of the distinct characteristics of NM, with respect to
epidemiology and risk factors, clinical presentation, histopathology,
molecular and dermoscopic aspects, and screening practices. The real
challenges are to find better biomarkers of aggressiveness and to know
whether the control of such aggressive melanomas can be influenced by
targeted interventions such as early detection, drug interventions and
preventive strategies.
Συγγραφείς:
Dessinioti, C.
Geller, A. C.
Whiteman, D. C.
Garbe, C. and
Grob, J. J.
Kelly, J. W.
Scolyer, R. A.
Rawson, V, R. and
Lallas, A.
Pellacani, G.
Stratigos, A. J.
Περιοδικό:
British Journal of Dermatology
