Τίτλος:
Impact of a 4-year antimicrobial stewardship program implemented in a
Greek tertiary hospital
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
This study aimed to investigate the effects of a 4-year antibiotic
stewardship program (ASP) in a tertiary hospital. We monitored data for
2015 (pre-intervention) and 2016-2019 (post-intervention) about
antibiotic consumption (DDD/100 bed days), Clostridioides difficile
infections (CDIs), resistance rates, length of stay (LOS), and annual
antibiotic costs. Significant reductions were observed for total
antibiotics/colistin/ carbapenems/quinolones/tigecycline consumption and
resistance rates of Pseudomonas aeruginosa, Klebsiella pneumoniae, and
vancomycin-resistant enterococci. Considerable reductions occurred for
LOS (4.18 [2015]/3.0 [2019] days), CDIs (1.47 [2015]/0.86 [2019]
per 1000 patients), antibiotic cost/patient (39.45(sic)
[2015]/23.69(sic) [2019]). The ASP was successful in reducing
antibiotic consumption, antibiotic costs, length of hospital stay, and
CDIs.
Συγγραφείς:
Chrysou, Konstantina
Zarkotou, Olympia
Kalofolia, Sofia and
Papagiannakopoulou, Panagiota
Mamali, Vasiliki
Chrysos, Georgios
and Themeli-Digalaki, Katina
Sypsas, Nikolaos
Tsakris,
Athanasios
Pournaras, Spyros
Περιοδικό:
European Journal of Clinical Microbiology & Infectious Diseases
Λέξεις-κλειδιά:
Antibiotic consumption; Antimicrobial stewardship; Clostridioides
difficile infections; Antibiotic costs; Length of hospital stay
DOI:
10.1007/s10096-021-04290-7
