Τίτλος:
Updates and Ongoing Challenges in Imaging of Multiple Myeloma: AJR
Expert Panel Narrative Review
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Advances in the understanding and treatment of multiple myeloma have led
to the need for more sensitive and accurate imaging of intramedullary
and extramedullary disease. This role of imaging is underscored by
recently revised imaging recommendations of the International Myeloma
Working Group (IMWG). This narrative review discusses these
recommendations from the IMWG for different disease stages, focusing on
advanced whole-body modalities, and addresses related challenges and
controversies. In the recommendations, whole-body low-dose CT is central
in initial patient assessment, replacing the conventional skeletal
survey. Although the recommendations favor MRI for diagnosis because of
its superior sensitivity and utility in identifying myeloma-defining
events, FDG PET/CT is recommended as the modality of choice for
assessing treatment response. Consensus opinions are offered regarding
the role of imaging in multiple myeloma for characterization of disease
distribution, determination of prognosis, and response evaluation.
Συγγραφείς:
Wu, Fangbai
Bernard, Stephanie
Fayad, Laura M.
Ilaslan,
Hakan
Messiou, Christina
Moulopoulos, Lia Angela
Mulligan,
Michael E.
Περιοδικό:
AJR. AMERICAN JOURNAL OF ROENTGENOLOGY
Εκδότης:
AMER ROENTGEN RAY SOC
Λέξεις-κλειδιά:
International Myeloma Working Group; multiple myeloma; PET/CT;
whole-body low-dose CT; whole-body MRI
DOI:
10.2214/AJR.21.25878
