Τίτλος:
Real-Time Passive Brain Monitoring System Using Near-Field Microwave Radiometry
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Near-field microwave radiometry has emerged as a tool for real-time passive monitoring of local brain activation, possibly attributed to local changes in blood flow that correspond to temperature and/or conductivity changes. The aim of this study is to design and evaluate a prototype system based on microwave radiometry intended to detect local changes of temperature and conductivity in depth in brain tissues. A novel radiometric system that comprises a four port total power Dicke-switch sensitive receiver that operates at 1.5 GHz has been developed. Methods and Results: The efficacy of the system was assessed through simulation and experiment on brain tissue mimicking phantoms under different setup conditions, where temperature and conductivity changes were accurately detected. In order to validate the radiometer's capability to sense low power signals occurring spontaneously from regions in the human brain, the somatosensory cortices of one volunteer were measured under pain-inducing psychophysiological conditions. The promising results from the initial in vivo measurements prove the system's potential for more extensive investigative trials. Conclusion and Significance: The significance of this study lies on the development of a compact and sensitive radiometer for totally passive monitoring of local brain activation as a potential complementary tool for contributing to the research effort for investigating brain functionality. © 1964-2012 IEEE.
Συγγραφείς:
Groumpas, E.
Koutsoupidou, M.
Karanasiou, I.S.
Papageorgiou, C.
Uzunoglu, N.
Περιοδικό:
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING
Εκδότης:
IEEE Computer Society
Λέξεις-κλειδιά:
Brain; Chemical activation; Radiometers; Radiometry; Tissue, Brain temperatures; Complementary tools; Conductivity changes; Microwave radiometry; Near-field microwave radiometry; Passive measurements; Real time monitoring; Somatosensory cortex, Microwaves, Article; brain tissue; conductance; electromagnetism; flow measurement; in vivo study; measurement; near field microwave radiometry; neuromonitoring; radiometry; simulation; temperature; body temperature; brain; equipment design; human; imaging phantom; microwave radiation; physiologic monitoring; physiology; procedures; radiometry; signal processing; somatosensory cortex, Body Temperature; Brain; Equipment Design; Humans; Microwaves; Monitoring, Physiologic; Phantoms, Imaging; Radiometry; Signal Processing, Computer-Assisted; Somatosensory Cortex
DOI:
10.1109/TBME.2019.2909994
