Τίτλος:
HLA ANTIGENS AND BRONCHOGENIC-CARCINOMA IN THE GREEK POPULATION
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
The distribution of HLA antigens was studied in 85 Greek patients with
bronchogenic carcinoma. Fifty-seven specific HLA antisera were used to
determine 27 HLA-A and B antigens, with the two-stage standard NIH
microlymphocytotoxicity assay. The results were compared with those in a
control group, consisting of 400 healthy individuals. In the whole group
of patients there was a significantly higher frequency of HLA-AW19 and
HLA-A29 (p < 0.003 and p < 0.006 respectively) and a lower frequency of
HLA-A2 and HLA-A3 (p < 0.014 and p < 0.006 respectively) than in the
control population. In patients with squamous cell carcinoma there was a
significantly higher frequency of HLA-AW19 and lower frequency of HLA-A2
(p < 0.02 and p < 0.05 respectively). In small cell carcinoma patients
there was a significantly lower frequency of HLA-A3 (p < 0.04) than
among the controls. In patients with adenocarcinoma no significant
change of HLA antigen frequencies was observed when compared to the
controls.
Συγγραφείς:
TOUMBIS, M
ZERVAS, J
ANAGNOSTOPOULOU, O
KONSTANTOPOULOS, K
and KRIMBENI, G
KOTSOVOULOU, V
FESSAS, F
Περιοδικό:
Acta Oncologica
Εκδότης:
Universitetsforlaget (Scandinavian University Press)
Λέξεις-κλειδιά:
HLA-ANTIGENS; BRONCHOGENIC CARCINOMA
DOI:
10.3109/02841869109092420
