Τίτλος:
INTRACERVICAL PROSTAGLANDIN-E(2) GEL FOR CERVICAL RIPENING AND LABOR
INDUCTION - WHAT IS THE APPROPRIATE DOSE
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
In order to evaluate a dose-related response of cervical ripening and
labor induction to a prostaglandin E2 (PGE2) gel, 110 women with
uncomplicated postdate pregnancies and unripe cervices received
intracervically 0.5 mg PGE2 (n = 40), 1.5 mg PGE2 (n = 35) or 2.5 mg
PGE2 (n= 35). The failure rate in terms of cervical ripening was similar
in all groups. Labor characteristics such as the duration of the latent
phase as well as the total length of labor, the cesarean-section rate,
instrumental deliveries and neonatal outcome were similar in all groups.
The number of women who required oxytocin for labor augmentation was
negatively correlated to the dose of PGE2 (P < 0.05). In addition, 3 out
of 35 women in the 2.5-mg group presented hypertonic uterine activity.
The increase in the dose of PGE2 gel did not increase the possibility
for a vaginal delivery, but reduced the requirement for oxytocin while
increasing hypertonic uterine action.
Συγγραφείς:
MINARETZIS, D
TSIONOU, C
PAPAGEORGIOU, I
MICHALAS, S and
ARAVANTINOS, D
Περιοδικό:
Gynecologic and Obstetric Investigation
Λέξεις-κλειδιά:
LABOR INDUCTION; PROSTAGLANDIN-E(2) GEL; INTRACERVICAL APPLICATION;
DIFFERENT DOSES; CERVICAL RIPENING
