Περίληψη:
The etiology of non-Hodgkin’s lymphoma (NHL) is not well understood. To
develop hypotheses on causes of this tumor, data from a population-based
case-control interview study of 1,867 white men (622 cases and 1,245
controls) in Iowa and Minnesota conducted during 1980-1983 were
examined. Subjects, or their next of kin, were interviewed to obtain
information on agricultural exposures, work history, medical conditions,
and family history. This analysis focuses on risks of NHL by occupation,
by industry, and by selected exposures. Although many comparisons were
made, few significant associations were observed. Small numbers and
limitations in exposure assessment, however, would tend to reduce
opportunities to detect associations. The strongest finding was with
various occupations that work in metals and metal products. The analysis
by exposure estimates also uncovered a significant association with
metals, but risks did not increase with estimated intensity of exposure.
Slightly elevated risks were also noted among persons employed as
painters and construction workers, agricultural and forestry workers,
printers and typesetters, funeral directors and embalmers, and dry
cleaners. Although the overall risks for benzene and other solvents were
small, they increased slightly with level of assigned exposure. Although
some associations may be due to chance, several of these occupations and
industries have been linked to lymphoma in other investigations and
deserve further attention.
Συγγραφείς:
BLAIR, A
LINOS, A
STEWART, PA
BURMEISTER, LF
GIBSON, R
and EVERETT, G
SCHUMAN, L
CANTOR, KP
