Περίληψη:
In the present study, neutrophil functions were examined in vitro in 40
patients suffering from fractures of the upper end of the femur
(trochanteric and subcapital). Adherence to nylon, serum chemotaxis, and
phagocytosis-bactericidal function were assayed. Three microbial
strains, namely, Staphylococcus aureus, S. epidermidis, and Pseudomonas
aeruginosa, were used for the experiments. Adherence of the patients’
neutrophils was found normal. On the contrary, the chemotactic ability
of the patients’ sera was inferior to that of healthy controls,
phagocytosis and bactericidal function were also significantly impaired
for all three bacterial strains. The results were independent of
fracture site (intracapsular or extracapsular), sex, and age. The
observed host defense disorders provide additional information that
helps to explain the increased susceptibility of these patients to
bacterial infections.
Συγγραφείς:
PAPADOPOULOS, NG
LIANOU, PE
LYRITIS, GP
PAPAVASSILIOU, JT
