Περίληψη:
We tested peripheral blood from 60 patients with definite multiple
sclerosis (MS) and 60 healthy controls for polymorphonuclear leukocyte
(PMNL) functions and found significant disorders in adherence (9.07%
+/- 8.18% far patients versus 28.97% +/- 5.76% for controls),
chemotaxis (18.32 +/- 3.1 for patients versus 30.49 +/- 4.52 for
controls), phagocytosis (73.6 +/- 25.25 for patients versus 111.2 +/-
25.7 for controls), and bactericidal action (10.35% +/- 5% for
patients versus 25.09% +/- 4.82% for controls). All differences were
significant (p < 0.001). We confirmed the results by retesting 3 to 8
months later. The depressed PMNL functions in MS patients may explain
their increased susceptibility to infections of the respiratory,
digestive, and urinary tracts.
Συγγραφείς:
PODIKOGLOU, DG
LIANOU, PE
TSAKANIKAS, CD
PAPAVASSILIOU, JT
