Περίληψη:
The Greek diet is characterized by a high total fat but low saturated
fat intake. In a hospital-based case-control study of female breast
cancer conducted in Athens (1989-91), 820 patients with confirmed cancer
of the breast were compared with 795 orthopaedic patient controls and
753 hospital visitor controls, matched to the cases by age and
interviewer. Diet was ascertained through a semiquantitative food
frequency questionnaire; macronutrient intakes were estimated from the
nutrient content of a selected typical portion size for each specified
food item, summed for all items. Logistic regression was used to analyse
the data, controlling for demographic and reproductive risk factors far
breast cancer as well as for total energy intake and mutual confounding
influences among nutrients. There was no significant or suggestive
association of total protein, total fat, categories of fat or total
carbohydrates with breast cancer risk. Thus, the mutually adjusted
relative risk per quintile and (in parenthesis) 95% confidence interval
were: for protein, 1.06 (0.94-1.20); saturated fat, 0.99 (0.89-1.11);
monounsaturated fat, 0.97 (0.88-1.07), polyunsaturated fat, 1.05
(0.97-1.13); and total carbohydrates, 1.03 (0.94-1.12). In alternative
analytical approaches only total protein appeared to be positively
associated to the occurrence of breast cancer with some consistency, but
the results were far from statistically significant. These findings do
not support a role for fat or other energy-generating nutrients in the
aetiology of breast cancer.
Συγγραφείς:
KATSOUYANNI, K
TRICHOPOULOU, A
STUVER, S
GARAS, Y and
KRITSELIS, A
KYRIAKOU, G
STOIKIDOU, M
BOYLE, P and
TRICHOPOULOS, D
