Τίτλος:
CYTOGENETIC STUDY OF 11 GASTRIC ADENOCARCINOMAS
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
We describe the cytogenetic findings in 11 gastric cancer cases. Nine
cases showed a variable number of numerical and structural aberrations,
while two cases had a normal karyotype. The chromosomes most frequently
involved are chromosome 3 in six cases, 6 in four cases, and 13 in three
cases. They mainly exhibited structural aberrations. An additional
segment on chromosome 3p was observed in three cases, while two cases
had a del(3q). A der(5) chromosome resulting from a translocation
between chromosomes 3 and 5 was observed in two cases. Both cases had
also a del(6q), a der(la), and an add(17p) chromosome as common
abnormalities. Deletion of 6q chromosome distal to band 6q21 was
observed in three cases. Trisomy 8 as a sole anomaly was found in one
case. Our cytogenetic findings are discussed in relation to the reported
in the literature data.
Συγγραφείς:
PANANI, AD
FERTI, A
MALLIAROS, S
RAPTIS, S
Περιοδικό:
CANCER GENETICS AND CYTOGENETICS
Εκδότης:
Elsevier Science Publ Co Inc, New York
DOI:
10.1016/0165-4608(94)00230-9
