Τίτλος:
EFFECT OF TRIMETHOPRIM-SULFAMETHOXAZOLE IN LANGERHANS CELL HISTIOCYTOSIS
- PRELIMINARY-OBSERVATIONS
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Twenty-three children with Langerhans’ cell histiocytosis (LCH) have
been treated with trimethoprim-sulphamethoxazole CT-S) in a 4-year
period. The child ren are classified in two main groups according to the
extent of their disease. Group A includes 16 children with single system
disease and group B, seven children with multisystem disease. All
patients were treated for 4 weeks to 3 months. The results of treatment
are evaluated in terms of response in individual organs involved. All
children with single system disease had a good response to the drug.
Children with multisystem disease had a good response to some organs but
a poorer outcome for the lungs and for the blood. These patients did not
respond even to conventional chemotherapy. (C) 1995 Wiley-Liss, Inc.
Συγγραφείς:
TZORTZATOUSTATHOPOULOU, F
XAIDARA, A
MIKRAKI, V
MOSCHOVI, M
and ARVANITIS, D
AGELOYIANNI, P
PRODROMOU, P
Περιοδικό:
Medical and Pediatric Oncology
Εκδότης:
Wiley-Liss, Inc.
Λέξεις-κλειδιά:
TRIMETHOPRIM-SULFAMETHOXAZOLE; LANGERHANS CELL HISTIOCYTOSIS;
THERAPEUTIC EFFECT
DOI:
10.1002/mpo.2950250205
