Τίτλος:
Recurrent condylomata acuminata: How routine immediate and delayed
hypersensitivity parameters might provide a clue to their
immunopathogenesis
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
In 30 male patients suffering from recurrent condylomata acuminata,
immediate hypersensitivity parameters (total IgE, PTT and prick tests)
and delayed hypersensitivity against seven recall antigens (multi test)
were studied. Thirty healthy male volunteers, matched in age, were the
controls. Significantly higher immediate hypersensitivity activity was
shown in the patient group. Qualitative evaluation of delayed type
hypersensitivity showed that controls had a positive test 16 times more
often than patients. A rather homogeneous suppression of delayed type
hypersensitivity was found in the patient group mainly as regards the
presumably most common antigens vs. the control group. This suppression
was proved to be related to disease duration. The hypothesis of a CD4+
Th-2 lymphocyte predominance in recurrent condylomata, owed to
longstanding or repetitive antigenic stimulation seems to adequately
explain the findings of the present study.
Συγγραφείς:
Kyriakis, KP
Balamotis, AK
KatsarouKatsari, A
Tosca, AD
Περιοδικό:
European Journal of Clinical Investigation
Εκδότης:
Blackwell Science Ltd Oxford, UK
Λέξεις-κλειδιά:
delayed hypersensitivity; immediate hypersensitivity; recurrent
condylomata
DOI:
10.1111/j.1365-2362.1995.tb01965.x
