Infant leukaemia after in utero exposure to radiation from Chernobyl

Επιστημονική δημοσίευση - Άρθρο Περιοδικού uoadl:3048430 20 Αναγνώσεις

Μονάδα:
Ερευνητικό υλικό ΕΚΠΑ
Τίτλος:
Infant leukaemia after in utero exposure to radiation from Chernobyl
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
THERE has been no documented increase in childhood leukaemia following
the Chernobyl accident. However, different forms of childhood leukaemia
may not be equally susceptible to radiation carcinogenesis. Infant
leukaemia is a distinct form associated with a specific genetic
abnormality. Outside the former Soviet Union, contamination resulting
from the Chernobyl accident has been highest in Greece and Austria and
high also in the Scandinavian countries(1-4). All childhood leukaemia
cases diagnosed throughout Greece since 1 January 1980 have been
recorded. Here we report that infants exposed in utero to ionizing
radiation from the Chernobyl accident had 2.6 limes the incidence of
leukaemia compared to unexposed children (95% confidence interval, 1.4
to 5.1; P approximate to 0.003), and those born to mothers residing in
regions with high radioactive fallout were at higher risk of developing
infant leukaemia. No significant difference in leukaemia incidence was
found among children aged 12 to 47 months. Preconceptional irradiation
had no demonstrable effect on leukaemia risk at any of the studied age
groups.
Έτος δημοσίευσης:
1996
Συγγραφείς:
Petridou, E
Trichopoulos, D
Dessypris, N
Flytzani, V and
Haidas, S
Kalmanti, M
Koliouskas, D
Kosmidis, H and
Piperopoulou, F
Tzortzatou, F
Περιοδικό:
Nature
Εκδότης:
MACMILLAN MAGAZINES LTD
Τόμος:
382
Αριθμός / τεύχος:
6589
Σελίδες:
352-353
Επίσημο URL (Εκδότης):
DOI:
10.1038/382352a0
Το ψηφιακό υλικό του τεκμηρίου δεν είναι διαθέσιμο.