Τίτλος:
Pregnancy results after ovum donation following one to seven embryo
transfers
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Objective: To determine whether failure to achieve pregnancy after
repeated ET after ovum donation was due to an endometrial defect or to
the embryo quality.
Design: Retrospective data analysis.
Setting: A private infertility center.
Patient(s): Four hundred sixty-seven donors (513 cycles) undergoing IVF
donating oocytes to 266 recipients (423 cycles).
Intervention(s): Hormonal endometrial preparation with increasing
dosages of valerate E(2) (2, 4, and 6 mg) and 100 mg of P.
Main Outcome Measure(s): Pregnancy rates (PRs) and abortion rates in
patients undergoing one to seven ETs after ovum donation.
Result(s): Pregnancy rates in recipients that had one or two ETs were
significantly higher (34.8%) compared with those of recipients having
three or more ETs (15.1%). Abortion rates were significantly higher
(54.5%) in recipients repeating more than three ETs than in the
recipients having one or two ETs (29.1%).
Conclusion(s): Recipients that had failed to establish a pregnancy after
two ETs had a lower PR in successive attempts, possibly because of a
defect of their endometrial lining.
Συγγραφείς:
Mantzavinos, T
Rizos, D
Dimitriadou, F
Arvaniti, K and
Kanakas, N
Voutsina, K
Περιοδικό:
Fertility and Sterility
Εκδότης:
AMER SOC REPRODUCTIVE MEDICINE
Λέξεις-κλειδιά:
oocyte donation; repeated embryo transfers; embryo quality; endometrial
lining
DOI:
10.1016/S0015-0282(16)58633-6
