Τίτλος:
Aggregation of childhood leukemia in geographic areas of Greece
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
A total of 872 children aged up to 14 years, who were diagnosed with
leukemia in Greece during the decade 1980-89, were allocated by place of
residence to the 601 administrative districts of the country. Evaluation
of spatial clustering was done using the Potthoff-Whittinghill method,
which validly assesses heterogeneity of leukemia risk among districts
with variable expected numbers of cases. There was highly significant
evidence for spatial clustering occurring particularly among children
living in urban and, to a lesser extent, semi-urban areas. The evidence
was stronger for children younger than 10 years old, applied also to
children in different five-year age groups, and persisted when cases of
acute lymphoblastic leukemia were analyzed separately These findings
provide support to the hypothesis that localized environmental exposures
could contribute to the etiology of childhood leukemia, but they cannot
distinguish between exposures of physical or chemical nature, nor can
they exclude socially conditioned patterns of exposure to infectious
agents.
Συγγραφείς:
Petridou, E
Alexander, FE
Trichopoulos, D
Revinthi, K and
Dessypris, N
Wray, N
Haidas, S
Koliouskas, D
Kosmidis, H
and Piperopoulou, F
Tzortzatou, F
Περιοδικό:
Cancer Causes and Control
Εκδότης:
RAPID SCIENCE PUBLISHERS
Λέξεις-κλειδιά:
childhood leukemia; environmental exposure; Greece; spatial clustering
DOI:
10.1023/A:1018480515690
