Περίληψη:
A significant increase in the frequency of isolation of Salmonella
enteritidis has been observed during recent years in Greece, parallelled
by an increasing rate of resistance of this organism to antibiotics, A
substantial proportion of ampicillin- and doxycycline-resistant isolates
exhibited cross-resistance to drugs of other classes, such as
sulfonamides and streptomycin. Isolates of human origin were overall
less resistant than those of animal or food-feed origin, Indeed, strains
associated with animal infections were characterized by the highest
rates of resistance to several antibiotics, These phenotypic data were
correlated with genotypic information concerning two distinct
populations: isolates from all sources that were resistant only to
ampicillin, the drug toward which resistance rates were highest, and a
control group of sensitive isolates, Ampicillin resistance was due to a
34-MDa conjugative plasmid, DNA fingerprinting by macrorestriction of
genomic DNA revealed two types, A and B, common to both
ampicillin-resistant and -sensitive strains, with 80 to 90% of strains
being of type A, However, a third type, C, was specific for the
sensitive population, representing 17% of those strains, Therefore,
although the majority of resistant isolates were genetically related to
sensitive ones, there existed a susceptible clone which had not acquired
any resistance traits.
Συγγραφείς:
Tassios, PT
Markogiannakis, A
Vatopoulos, AC
KAtsanikou, E
and Velonakis, EN
KoureaKremastinou, J
Legakis, NJ
