Preliminary evaluation of the potential prognostic value of serum levels of immunoglobulins (IgA, IgM, IgG, IgE) in patients with gastric cancer

Επιστημονική δημοσίευση - Άρθρο Περιοδικού uoadl:3050347 10 Αναγνώσεις

Μονάδα:
Ερευνητικό υλικό ΕΚΠΑ
Τίτλος:
Preliminary evaluation of the potential prognostic value of serum levels
of immunoglobulins (IgA, IgM, IgG, IgE) in patients with gastric cancer
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Sixty patients with advanced gastric carcinoma who refused to receive
cytotoxic chemotherapy were examined for serum immunoglobulin levels
(Igc, IgM, IgA, IgE). Three samples were obtained every two months
thereafter The group of patients who had above-normal values of one or
more of the examined immunoglobulins had a longer survival than the
other (p<0.024). Immunoglobulin values were independent of the
Helicobacter pylori antibody titer and of acute phase reactants. it is
concluded that survival potentially correlates with serum immunoglobulin
levels. Further studies including larger numbers of patients and
correlating serum immunoglobulin levels with specific clinical
parameters are needed to establish the prognostic role of serum
immunoglobulins in patients with gastric carcinoma.
Έτος δημοσίευσης:
1998
Συγγραφείς:
Tsavaris, N
Tsigalacis, D
Kosmas, C
Koufos, C and
Vaiopoulos, G
Tzivras, M
Kouraklis, G
Papadimas, V and
Georgoulis, V
Archimandritis, A
Sechas, M
Περιοδικό:
International Journal of Biological Markers
Εκδότης:
Wichtig Editore
Τόμος:
13
Αριθμός / τεύχος:
2
Σελίδες:
87-91
Λέξεις-κλειδιά:
gastric cancer; immunoglobulins; prognosis survival
Επίσημο URL (Εκδότης):
DOI:
10.1177/172460089801300204
Το ψηφιακό υλικό του τεκμηρίου δεν είναι διαθέσιμο.