Τίτλος:
Inhomogeneity in response to air pollution in European children (PEACE
project)
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Objectives-The PEACE study is a multicentre panel study of the acute
effects of particles with a 50% cut off aerodynamic diameter of 10 mu m
(PM10), black smoke (BS), sulphur dioxide (SO2), and nitrogen dioxide
(NO2) on respiratory health of children with chronic respiratory
symptoms. In the complete panels no consistent association between air
pollution and respiratory health was found. The study evaluated whether
potentially more sensitive subgroups in the panels did show effects of
air pollution.
Methods-To evaluate heterogeneity in response to air pollution, effect
estimates of air pollution on peak expiratory flow (PEF) and respiratory
symptoms were calculated in subgroups based on presence of chronic
respiratory symptoms, use of respiratory medication, atopy, sex, and
baseline lung function.
Results-The association between PEF and air pollution was positive in
asthmatic children who used respiratory medication whereas the
associations tended to be negative in children who did not use
respiratory medication selected only on cough. No consistent association
was found among asthmatic children who did not use medication. The
association between daily prevalence of symptoms and concentrations of
air pollution was not different between these subgroups.
Conclusion-None of the predefined potentially more sensitive subgroups
showed a consistent association between air pollution, PEF, and
respiratory symptoms.
Συγγραφείς:
Roemer, W
Clench-Aas, J
Englert, N
Hoek, G
Katsouyanni,
K
Pekkanen, J
Brunekreef, B
Περιοδικό:
Annals of Occupational and Environmental Medicine
Εκδότης:
BMJ Publishing Group
Λέξεις-κλειδιά:
epidemiology; air pollution; children
