Περίληψη:
A biodegradable polymer of DL-dilactide that facilitates release of
ciprofloxacin or pefloxacin at levels exceeding MICs for the causative
microorganisms of chronic osteomyelitis is described. Duration and peak
of release were found to depend on the molecular weight of the polymer.
Its characteristics make it promising for treating chronic bone
infections.
Συγγραφείς:
Kanellakopoulou, K
Kolia, M
Anastassiadis, A
Korakis, T and
Giamarellos-Bourboulis, EJ
Andreopoulos, A
Dounis, E and
Giamarellou, H