Τίτλος:
Microvascular abnormalities in Sjogren's syndrome: nailfold
capillaroscopy
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Objective. To describe microvascular abnormalities by nailfold
capillaroscopy in patients with primary Sjogren’s syndrome (SS) with or
without Raynaud’s phenomenon (RP) and those with anticentromere
antibodies (ACA).
Methods. Forty patients with SS (14 without RP, 16 with RP, 10 with
ACA), 20 patients with scleroderma (SSc) (10 with limited and 10 with
diffuse disease) (disease control group) and 40 healthy controls
(control group) were evaluated by nailfold capillaroscopy.
Results. Capillaroscopic abnormalities in SS ranged from non-specific
findings (crossed capillaries) to more specific findings (confluent
haemorrhages and pericapillary haemorrhages) or scleroderma-type
findings. SS patients with RP presented capillary abnormalities in
higher frequency than patients without RP. The majority of SS patients
with ACA (80%) presented scleroderma-type findings.
Conclusion. Nailfold capillaroscopy can be used as a simple nan-invasive
method to evaluate the microvascular abnormalities in SS patients,
especially in those with RP and those with ACA.
Συγγραφείς:
Tektonidou, M
Kaskani, E
Skopouli, FN
Moutsopoulos, HM
Περιοδικό:
The Lancet Rheumatology
Εκδότης:
Oxford University Press
Λέξεις-κλειδιά:
Sjogren’s syndrome; nailfold capillaroscopy; anticentromere antibodies;
Raynaud’s phenomenon; scleroderma
DOI:
10.1093/rheumatology/38.9.826
