Τίτλος:
Bacteroides, Prevotella, and Porphyromonas species: a review of
antibiotic resistance and therapeutic options
Περίληψη:
Recent basic and clinical research efforts have shed more light on the
taxonomy, microbiology, epidemiology, antimicrobial susceptibility and
treatment of Bacteroides, Prevotella, and Porphyromonas species. Of all
anaerobic bacteria, Bacteroides is the most frequently isolated pathogen
from clinical specimens, including blood. Bacterioides, Prevotella
and/or Porphyromonas species have been isolated from clinical specimens
in cases of infection from almost all anatomic sites. Several
multicentre surveys have documented an alarming gradual increase of
resistance rates of Bacteroides, Prevotella and Porphyromonas species
worldwide. Antimicrobial agents active against >99% of clinical
isolates of Bacteroides are metronidazole, chloramphenicol and
carbapenems. Agents active against 95-99% of bacteroides fragilis
isolates are the beta-lactam/beta-lactamase inhibitor combinations. .
fragilis group species other than B. fragilis are more likely to be
resistant to beta-lactam/beta-lactamase inhibitor combinations than B.
fragilis. (C) 2000 Elsevier Science B.V. and International Society of
Chemotherapy. All rights reserved.
