Τίτλος:
Behcet's disease in a patient with chronic myelogenous leukemia under
hydroxyurea treatment: A case report and review of the literature
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Behcet’s disease (BD) is a chronic, relapsing vasculitis of unknown
etiology. Its association with chronic myelogenous leukemia (CML) is
extremely rare, and typical manifestations of an were observed in a very
few patients with CML, mainly under interferon-alpha (IFN-alpha)
treatment. Skin pathergy test, being positive in about 50% of patients
with an, is also positive in some IFN-alpha -treated patients with CML
without any evidence of an symptoms. We describe a 62-year-old woman
with CML who developed characteristic features of an, including a
positive skin hyperactivity test, during treatment with hydroxyurea.
Hydroxyurea has been implicated in the appearance of skin vasculitic
ulceration, but this is the first case, according to our knowledge,
where the development of ED was observed during hydroxyurea maintenance
in the chronic phase of CML. (C) 2001 Wiley-Liss, Inc.
Συγγραφείς:
Vaiopoulos, G
Terpos, E
Viniou, N
Nodaros, K
Rombos, J
and Loukopoulos, D
Περιοδικό:
American Journal of Hematology
Εκδότης:
Wiley-Liss, Inc.
Λέξεις-κλειδιά:
Behcet’s disease; chronic myelogenous leukemia (CML); skin pathergy
test; interferon-alpha (IFN-alpha); hydroxyurea
DOI:
10.1002/1096-8652(200101)66:1<57::AID-AJH1010>3.0.CO;2-3
