Τίτλος:
Transmission dynamics of sars-cov-2 during an outbreak in a roma community in thessaly, greece—control measures and lessons learned
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
A COVID-19 outbreak occurred among residents of a Roma settlement in Greece (8 April– 4 June 2020). The aim of this study was to identify factors associated with an increased risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and to evaluate the effectiveness of control measures implemented. Data were analyzed from individuals that were tested for SARS-CoV-2 during contact tracing, population screening or hospital visits. RT-PCR was used for the detection of SARS-CoV-2 in oropharyngeal samples. Risk factors for household secondary attack rates (SAR) and hospitalization with COVID-19 were examined using chi-square tests, Fisher’s exact tests and logistic regression analyses. During the outbreak, 142 cases, 20 hospitalizations and 1 death were recorded, with a total of 2273 individuals tested. The risk of hospitalization was associated with age (OR: 1.04, 95% CI: 1.02–1.07) and Cycle threshold (Ct) values (OR for a decrease in Ct values by 1: 1.18, 95% CI: 1.07–1.31). Household SAR was estimated at 38.62% (95% CI: 32.50%– 45.01%). After the designation of an isolation facility for cases, household SAR declined from 74.42% to 31.03%. Household size was associated with the risk of infection (OR: 2.65, 95% CI: 1.00–7.07). The presence of COVID-19 symptoms among index cases was correlated with higher transmission (OR: 23.68, 95% CI 2.21–253.74) in multivariate analysis, while age was found to be associated with SAR only in univariate analysis. Roma communities can be particularly vulnerable to the spread of SARS-CoV-2. In similar settings, symptomatic cases are more important transmitters of SARS-CoV-2. Within these communities, immediate measures should be implemented to mitigate disease spread. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.
Συγγραφείς:
Koureas, M.
Speletas, M.
Bogogiannidou, Z.
Babalis, D.
Pinakas, V.
Pinaka, O.
Komnos, A.
Tsoutsa, S.
Papadamou, G.
Kyritsi, M.A.
Vontas, A.
Nakoulas, V.
Sapoynas, S.
Kanellopoulos, N.
Kalompatsios, D.
Papadouli, V.
Dadouli, K.
Soteriades, S.
Mina, P.
Mouchtouri, V.A.
Anagnostopoulos, L.
Stamoulis, K.E.
Agorastos, K.
Petinaki, E.A.
Prezerakos, P.
Tsiodras, S.
Hadjichristodoulou, C.
Περιοδικό:
International Journal of Environmental Research and Public Health
Λέξεις-κλειδιά:
COVID-19; disease control; disease spread; disease transmission; disease treatment; health risk; household survey; public health; vulnerability, adolescent; adult; aged; Article; chi square test; child; comorbidity; contact examination; controlled study; coronavirus disease 2019; cycle threshold value; demography; disease transmission; female; Fisher exact test; Greece; hospitalization; household; human; infant; isolation facility; logistic regression analysis; major clinical study; male; mass screening; nonhuman; prevalence; real time polymerase chain reaction; risk factor; secondary attack rate; Severe acute respiratory syndrome coronavirus 2; epidemic; epidemiology; Romani (people), Greece; Italy; Lazio; Roma [Lazio]; Rome, SARS coronavirus, COVID-19; Disease Outbreaks; Greece; Humans; Roma; SARS-CoV-2
DOI:
10.3390/ijerph18062878
