Τίτλος:
Desmettianosides A and B, bisdesmosidic furostanol saponins with molluscicidal activity from Yucca desmettiana
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Bioactivity-guided separation of the aqueous methanolic extract of Yucca desmettiana leaves, which in a preliminary screening exhibited significant molluscicidal activity, led to the isolation and structure elucidation of two new steroidal saponins (1 and 2). The structures of desmettianosides A and B, identified as bisdesmosidic furostanol glycosides with six and five sugar units, respectively, were established by detailed spectroscopic analyses of their NMR and MS data. Compounds 1 and 2 exhibited high molluscicidal activity against Biomphalaria alexandrina snails with LC 100 values of 6 and 11 mg/L, respectively.
Συγγραφείς:
Diab, Y.
Ioannou, E.
Emam, A.
Vagias, C.
Roussis, V.
Λέξεις-κλειδιά:
desmettianoside A; desmettianoside B; saponin; unclassified drug, article; biomphalaria alexandrina; drug structure; nonhuman; snail; yucca; Yucca desmettiana, Animals; Biomphalaria; Methanol; Molluscacides; Plant Leaves; Saponins; Water; Yucca, Biomphalaria alexandrina; Gastropoda
DOI:
10.1016/j.steroids.2012.02.014
