Τίτλος:
Polyphasic identification and susceptibility to seven antifungals of 102 Aspergillus isolates recovered from immunocompromised hosts in Greece
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
In this study, the first such study in Greece, we used polyphasic identification combined with antifungal susceptibility study to analyze Aspergillus clinical isolates comprising 102 common and rare members of sections Fumigati, Flavi, Terrei, Nidulantes, Nigri, Circumdati, Versicolores, and Usti. High amphotericin B MICs (>2 μg/ml) were found for 17.6% of strains. Itraconazole, posaconazole, and voriconazole MICs of >4 μg/ml were shown in 1%, 5%, and 0% of the isolates, respectively. Anidulafungin, micafungin, and caspofungin minimum effective concentrations (MECs) of ≥2 μg/ml were correspondingly recorded for 4%, 9%, and 33%, respectively, of the strains. Copyright © 2011, American Society for Microbiology. All Rights Reserved.
Συγγραφείς:
Arabatzis, M.
Kambouris, M.
Kyprianou, M.
Chrysaki, A.
Foustoukou, M.
Kanellopoulou, M.
Kondyli, L.
Kouppari, G.
Koutsia-Karouzou, C.
Lebessi, E.
Pangalis, A.
Petinaki, E.
Stathi, A.
Trikka-Graphakos, E.
Vartzioti, E.
Vogiatzi, A.
Vyzantiadis, T.-A.
Zerva, L.
Velegraki, A.
Περιοδικό:
Antimicrobial Agents and Chemotherapy
Λέξεις-κλειδιά:
amphotericin B; anidulafungin; caspofungin; itraconazole; micafungin; posaconazole; voriconazole, analysis of variance; antifungal susceptibility; article; aspergillosis; Aspergillus; Aspergillus circumdatus; Aspergillus flavus; Aspergillus fumigatus; Aspergillus nidulans; Aspergillus niger; Aspergillus terreus; Aspergillus ustus; Aspergillus versicolores; bone nail; bronchus secretion; fungal strain; fungus identification; fungus isolation; Greece; hospital patient; human; immunocompromised patient; liver biopsy; lung biopsy; lung lavage; major clinical study; maxillary bone nail; minimum inhibitory concentration; morphology; nasal biopsy; nucleotide sequence; peritoneal fluid; priority journal; skin biopsy, Antifungal Agents; Aspergillus; Drug Resistance, Fungal; Greece; Humans; Immunocompromised Host; Microbial Sensitivity Tests
DOI:
10.1128/AAC.01491-10
