Τίτλος:
Clinical management of patients with genetic obesity during COVID-19 pandemic: position paper of the ESE Growth & Genetic Obesity COVID-19 Study Group and Rare Endo-ERN main thematic group on Growth and Obesity
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
This article aims to provide guidance on prevention and treatment of COVID-19 in patients with genetic obesity. Key principals of the management of patients with genetic obesity during COVID-19 pandemic for patients that have contracted COVID-19 are to be aware of: possible adrenal insufficiency (e.g., POMC deficiency, PWS); a more severe course in patients with concomitant immunodeficiency (e.g., LEP and LEPR deficiency), although defective leptin signalling could also be protective against the pro-inflammatory phenotype of COVID-19; disease severity being masked by insufficient awareness of symptoms in syndromic obesity patients with intellectual deficit (in particular PWS); to adjust medication dose to increased body size, preferably use dosing in m2; the high risk of malnutrition in patients with Sars-Cov2 infection, even in case of obesity. Key principals of the obesity management during the pandemic are to strive for optimal obesity management and a healthy lifestyle within the possibilities of the regulations to prevent weight (re)gain and to address anxiety within consultations, since prevalence of anxiety for COVID-19 is underestimated. © 2021, The Author(s).
Συγγραφείς:
De Groot, C.J.
Poitou Bernert, C.
Coupaye, M.
Clement, K.
Paschou, S.A.
Charmandari, E.
Kanaka-Gantenbein, C.
Wabitsch, M.
Buddingh, E.P.
Nieuwenhuijsen, B.
Marina, L.
Johannsson, G.
Van Den Akker, E.L.T.
Περιοδικό:
Endocrine Development
Λέξεις-κλειδιά:
adrenal insufficiency; body size; coronavirus disease 2019; disease severity; genetic obesity; high risk population; human; infection risk; obesity; pandemic; patient care; phenotype; priority journal; quarantine; Review; risk assessment; anxiety; disease management; genetics; healthy lifestyle; obesity, Anxiety; COVID-19; Disease Management; Healthy Lifestyle; Humans; Obesity; Pandemics
DOI:
10.1007/s12020-021-02619-y
