Τίτλος:
Implant infections after breast reconstruction surgery following mastectomy: Experience from a Greek breast unit
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
BACKGROUND: Despite the dominance of implant-based breast reconstruction after mastectomy, during recent years, it has been correlated to some complications. The aim of this study is to present the Greek experience about management of implant infections after breast reconstructions and to investigate the relationship between possible risk factors and breast pocket fluid cultures. METHODS: In total, 260 patients underwent implant-based breast reconstruction due to breast cancer in our center from 2016 until 2020. 46 patients, that underwent implant or expander replacement after breast reconstruction due to mastectomy were included in the present study. RESULTS: 260 patients underwent breast reconstruction in our center and in 46 (18%) of them an implant replacement was required. 21 patients (8%) presented clinically with an implant infection, but 12 of them (5%) had positive cultures from the breast pocket fluid. On the contrary, 25 patients (10%) presented no clinical signs of implant infection, but 5 of them (2%) had a positive culture. In addition, we demonstrated a correlation between implant infection and positive cultures (p = 0.009), along with an association between chemotherapy before implant placements and negative cultures (p = 0.035). Finally, the most common pathogen was Staphylococcus epidermidis (29%), followed by Escherichia coli (24%) and Staphylococcus aureus (18%). CONCLUSION: Implant infection still remains a very serious complication after breast reconstruction surgery. The establishment of a therapeutic protocol, with specific antimicrobial and surgical targets seems as an effective strategy against implant infections. © 2022 - IOS Press. All rights reserved.
Συγγραφείς:
Michalopoulos, N.V.
Frountzas, M.
Karathanasis, P.
Theodoropoulos, C.
Kolia, A.
Zografos, C.G.
Triantafyllou, T.
Larentzakis, A.
Danias, N.
Zografos, G.C.
Περιοδικό:
Breast Diseases
Λέξεις-κλειδιά:
adult; aged; Article; bacterium culture; breast reconstruction; correlational study; Escherichia coli; female; human; infection risk; major clinical study; mastectomy; mastitis; nonhuman; personal experience; risk factor; Staphylococcus aureus; Staphylococcus epidermidis; adverse event; bacterial infection; bacterium; breast augmentation; breast endoprosthesis; breast reconstruction; breast tumor; classification; Greece; mastectomy; microbiology; middle aged; pathogenicity; postoperative complication; reoperation; retrospective study, Adult; Aged; Bacteria; Bacterial Infections; Breast Implantation; Breast Implants; Breast Neoplasms; Female; Greece; Humans; Mammaplasty; Mastectomy; Middle Aged; Postoperative Complications; Reoperation; Retrospective Studies; Risk Factors
