Τίτλος:
Risk factors for venous thromboembolism in patients with small cell lung cancer
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Background/Aim: Small cell lung cancer (SCLC) accounts for 13% of all lung cancers. Venous thromboembolism (VTE) is a frequent complication. The purpose of this study was to investigate the incidence and risk factors for VTE in SCLC patients. Patients and methods: Retrospective analysis of patients with histologically confirmed SCLC treated between January 2015 and June 2018 at Sotiria General Hospital, Athens, Greece. Results: Two hundred and seventeen patients were included in the analysis. The incidence of VTE was 4.1%. Increased body mass index (BMI) was correlated with the development of VTE. Moreover, VTE appeared more frequently in patients with major vessel infiltration and with poor Eastern Cooperative Oncology Group Performance Status. Other factors, including gender, age, stage, presence of metastasis, treatment, immobilization, anticoagulation, comorbidities, and laboratory values did not correlate with the development of VTE. Conclusion: Factors associated with the development of VTE were BMI, major vessel infiltration and PS. Identifying factors that predispose to VTE could help physicians detect high-risk patients who would benefit from prophylactic anticoagulation therapy. © 2021 International Institute of Anticancer Research. All rights reserved.
Συγγραφείς:
Dimakakos, E.
Livanios, K.
Vathiotis, I.
Gomatou, G.
Gkiozos, I.
Kotteas, E.
Kainis, E.
Syrigos, K.
Περιοδικό:
ANTICANCER RESEARCH
Εκδότης:
International Institute of Anticancer Research
Λέξεις-κλειδιά:
anticoagulant agent; antineoplastic agent; hemoglobin, aged; anticoagulant therapy; Article; body mass; cancer chemotherapy; cancer patient; cancer radiotherapy; cancer survival; Charlson Comorbidity Index; comorbidity; controlled study; current smoker; deep vein thrombosis; disease risk assessment; distant metastasis; ex-smoker; female; Greece; human; incidence; khorana risk score; leukocyte count; lung embolism; major clinical study; male; medical record review; obesity; platelet count; priority journal; retrospective study; risk factor; scoring system; small cell lung cancer; venous thromboembolism; complication; lung tumor; middle aged; risk factor; small cell lung cancer; venous thromboembolism, Aged; Anticoagulants; Body Mass Index; Female; Humans; Lung Neoplasms; Male; Middle Aged; Retrospective Studies; Risk Factors; Small Cell Lung Carcinoma; Venous Thromboembolism
DOI:
10.21873/anticanres.14911
