Περίληψη:
Aims: The aim of the study was to investigate the association between type-2 diabetes mellitus, other underlying diseases and obesity with the outcomes of critically ill Covid-19 patients in Greece. Methods: In this retrospective observational multi-centre study, data and outcomes of 90 RNA 2109-nCoV confirmed critically ill patients from 8 hospitals throughout Greece, were analysed. All reported information stand through April 13th 2020. Results: The median age of the patients was 65.5 (IQR 56–73), majority were male (80%) and obesity was present in 34.4% of patients most prevalent to younger than 55 years. Hypertension was the prevailing comorbidity (50%), followed by cardiovascular diseases (21.1%) and type-2 diabetes (18.9%). At admission, common symptoms duration had a median of 8 (IQR 5–11) days. A 13.3% of the patients were discharged, 53.4% were still in the ICUs and 28.9% deceased who were hospitalised for fewer days than the survivors [6 (IQR 3–9) vs. 9 (IQR 7–14.5) respectively]. Aging was not a risk factor but diabetes deteriorates the outcomes. Obesity poses a suggestive burden as it was more notable in deceased versus survivors. Conclusions: Type 2 diabetes and obesity may have contributed to disease severity and mortality in COVID-19 critically ill patients in Greece. © 2020 Elsevier B.V.
Συγγραφείς:
Halvatsiotis, P.
Kotanidou, A.
Tzannis, K.
Jahaj, E.
Magira, E.
Theodorakopoulou, M.
Konstandopoulou, G.
Gkeka, E.
Pourzitaki, C.
Kapravelos, N.
Papoti, S.
Sileli, M.
Gogos, C.
Velissaris, D.
Markou, N.
Stefanatou, E.
Vlachogianni, G.
Aimoniotou, E.
Komnos, A.
Zafeiridis, T.
Koulouvaris, P.
Armaganidis, A.
Bamias, A.
Dimopoulos, G.
Λέξεις-κλειδιά:
adult; aged; aging; Article; clinical feature; comorbidity; coronavirus disease 2019; critical illness; critically ill patient; demography; disease burden; disease duration; disease severity; female; Greece; hospital admission; hospital discharge; human; hypertension; infection risk; intensive care unit; length of stay; major clinical study; male; mortality; non insulin dependent diabetes mellitus; obesity; observational study; retrospective study; Betacoronavirus; clinical trial; complication; Coronavirus infection; critical illness; diabetes mellitus; hospitalization; isolation and purification; middle aged; mortality; multicenter study; obesity; pandemic; pathophysiology; prognosis; risk factor; survival rate; virology; virus pneumonia, Aged; Betacoronavirus; Comorbidity; Coronavirus Infections; Critical Illness; Diabetes Mellitus; Female; Greece; Hospitalization; Humans; Male; Middle Aged; Obesity; Pandemics; Pneumonia, Viral; Prognosis; Retrospective Studies; Risk Factors; Survival Rate
