Τίτλος:
Olive Oil Polyphenols in Neurodegenerative Pathologies
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
Neurodegenerative diseases lead to the death of nerve cells in the brain or the spinal cord. A wide range of diseases are included within the group of neurodegenerative disorders, with the most common ones being dementia, Alzheimer’s, and Parkinson’s diseases. Millions of older people are suffering from such pathologies. The global increase of life expectancy unavoidably leads to a consequent increase in the number of people who will be at some degree affected by neurodegenerative-related diseases. At this moment, there is no effective therapy or treatment that can reverse the loss of neurons. A growing number of studies highlight the value of the consumption of medical foods, and in particular olive oil, as one of the most important components of the Mediterranean diet. A diet based on extra virgin olive oil seems to contribute toward the lowering of risk of age-related pathologies due to high phenol concentration. The link of a polyphenol found in extra virgin olive oil, namely, tyrosol, with the protein tyrosinase, associated to Parkinson’s disease is underlined as a paradigm of affiliation between polyphenols and neurodegenerative disorders. © Springer Nature Switzerland AG 2020.
Συγγραφείς:
Salis, C.
Papageorgiou, L.
Papakonstantinou, E.
Hagidimitriou, M.
Vlachakis, D.
Περιοδικό:
Advances in Experimental Medicine and Biology
Λέξεις-κλειδιά:
amyloid beta protein; amyloid beta protein[1-40]; amyloid beta protein[1-42]; caffeic acid; donepezil; ferulic acid; galantamine; glutamate receptor antagonist; hydroxytyrosol; oleuropein; olive oil; para coumaric acid; pinoresinol; polyphenol; rivastigmine; tau protein; tyrosol; vanillic acid; 4-hydroxyphenylethanol; olive oil; phenethyl alcohol; polyphenol, Alzheimer disease; amyotrophic lateral sclerosis; cell death; chemical composition; degenerative disease; dietary intake; disease predisposition; human; Huntington chorea; neurofibrillary tangle; nonhuman; Parkinson disease; priority journal; protein aggregation; protein misfolding; substantia nigra; chemistry; degenerative disease; Mediterranean diet, Diet, Mediterranean; Humans; Neurodegenerative Diseases; Olive Oil; Phenylethyl Alcohol; Polyphenols
DOI:
10.1007/978-3-030-32633-3_12
