Τίτλος:
Polyclonal predominance of concurrently producing OXA-23 and OXA-58 carbapenem-resistant Acinetobacter baumannii strains in a pediatric intensive care unit
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
We report a predominance (64.7%) of polyclonal carbapenem-resistant Acinetobacter baumannii (CRAB) strains concurrently producing OXA-23 and OXA-58 carbapenemases in a pediatric intensive care unit in an endemic area. This is the first report of emergence of such double-OXA CRAB strains in a single unit worldwide. © 2019, Springer Nature B.V.
Συγγραφείς:
Karampatakis, T.
Tsergouli, K.
Politi, L.
Diamantopoulou, G.
Iosifidis, E.
Antachopoulos, C.
Karyoti, A.
Sdougka, M.
Tsakris, A.
Roilides, E.
Περιοδικό:
Current Molecular Biology Reports
Εκδότης:
SPRINGER NETHERLANDS
Λέξεις-κλειδιά:
aminoglycoside antibiotic agent; beta lactam antibiotic; carbapenem; carbapenemase; cotrimoxazole; imipenem; meropenem; OXA 23 carbapenemase; OXA 58 carbapenemase; tetracycline; unclassified drug; antiinfective agent; bacterial protein; beta lactamase; carbapenem derivative; carbapenemase, antibiotic sensitivity; Article; bacterial metabolism; bacterial strain; carbapenem resistant Acinetobacter baumannii; controlled study; enzyme synthesis; minimum inhibitory concentration; molecular epidemiology; multidrug resistance; nonhuman; pediatric intensive care unit; species dominance; Acinetobacter baumannii; antibiotic resistance; drug effect; human; immunology; metabolism; microbial sensitivity test; pediatric intensive care unit, Acinetobacter baumannii; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Carbapenems; Drug Resistance, Bacterial; Humans; Intensive Care Units, Pediatric; Microbial Sensitivity Tests
DOI:
10.1007/s11033-019-04744-4
