Τίτλος:
l-Thyroxine induces thermotolerance in yeast
Γλώσσες Τεκμηρίου:
Αγγλικά
Περίληψη:
The cellular stress response (CSR) is a universal inducible reaction modulated, among others, by heat, drugs, and hormones. We aimed to investigate the role of l-thyroxine (T4) on the heat shock (HS) response in Saccharomyces cerevisiae. The CSR was evaluated by determining growth and viability of post-logarithmic phase grown yeast cultures after HS at 53 °C for 30 min. We found that long-term T4 exposure can induce a dose-dependent and Hsp90 and H+ trafficking-related thermotolerance in yeast. © 2019, Cell Stress Society International.
Συγγραφείς:
Papamichael, K.
Delitheos, B.
Mourouzis, I.
Pantos, C.
Tiligada, E.
Περιοδικό:
Cell Stress and Chaperones
Εκδότης:
Springer Science and Business Media B.V.
Λέξεις-κλειδιά:
heat shock protein 90; HSP82 protein, S cerevisiae; proton transporting adenosine triphosphatase; Saccharomyces cerevisiae protein; thyroxine, cell survival; drug effect; heat tolerance; metabolism; physiology; Saccharomyces cerevisiae, Cell Survival; HSP90 Heat-Shock Proteins; Proton-Translocating ATPases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Thermotolerance; Thyroxine
DOI:
10.1007/s12192-019-00978-0
