Περίληψη:
Chorion is the major component of silkmoth eggshell. More than 95% of
its dry mass consists of the A and B families of low molecular weight
structural proteins, which have remarkable mechanical and chemical
properties, and protect the oocyte and the del eloping embryo from the
environment. We present data from negative staining, Congo red binding,
X-ray diffraction, Fourier transform-Raman, attenuated total reflectance
infrared spectroscopy and modelling studies of a synthetic peptide
analogue of a part of the central domain of the B family of silkmoth
chorion proteins, indicating that this peptide folds and self-assembles,
forming amyloid-like fibrils, These results support further our
proposal, based on experimental data from a synthetic peptide analogue
of the central domain of the A family of chorion proteins, that silkmoth
chorion is a natural, protective amyloid [Iconomidou et a.,, FEBS
Lett, 479 (2000) 141-145].: (C) 2001 Federation of European Biochemical
Societies, Published by Elsevier Science B.V. All rights reserved.
Συγγραφείς:
Iconomidou, VA
Chryssikos, GD
Gionis, V
Vriend, G and
Hoenger, A
Hamodrakas, SJ
